Forum - Recent Topics

Rupert Spira clarity on Grieving

Josh Lamaro — Fri, 31 Oct 2025 03:58:40 +0000

Rupert is clear coming from the nature of awareness when addressing the arising emotion of grief:

https://www.youtube.com/watch?v=bQrs9U1yGUc

The NAD+ Infusion Scam

Josh Lamaro — Wed, 27 Jul 2022 06:25:09 +0000

One of the fastest moving trends in the "high end" health space at present is IV infusion therapy of various types, be it vitamins, methylene blue, or more recently, NAD+

There is certainly research claiming that IV doses are absorbed well. eg: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6751327/ , but this paper also notes that the researchers did no analysis on the fate of the NAD+ infused.

Regarding that fate, I reproduce a hyperlipid comment in full here

> Adding extra NAD+ should increase the NAD+/NADH ratio, making it easier to put an electron back through complex I without transferring it to oxygen, it just regenerates NADH.

> ROS generation occurs during RET when the NAD+/NADH ratio is low. Whether this is a good or a bad thing depends on how you view ROS and how pathological a person's core food choices have been.

> Certainly niacin is also a ketone mimetic and a FFA release inhibitor so there is a lot going on with this particular precursor.

Of course, Petro is biased, in that "pathological" usually revolves around insulin.

A relevant post here. Quotes below.

> The correct pathway for the metabolism of glucose without insulin is to lactate without any overall depletion of cytoplasmic NAD+

> Lactate can then be taken up by mitochondria exactly as ketones are. Lactate will, in the mitochondria, be reconverted to pyruvate, depleting mitochondrial NAD+ in exactly the same way as the conversion of BHB to AcAc does. Equally this happen right next door to complex I, just waiting to regenerate NAD+ and keep that NAD+:NADH ratio nice and high.

> The whole point of the glycerophosphate shuttle (in Protons terms) is to facilitate insulin signalling.

> Loss of the four pumped protons due to bypassing complex I and using mtG3Pdh instead as part of insulin signalling appears perfectly reasonable under conditions of active caloric ingress.

> Sustained insulin signalling causes sustained loss of cytoplasmic NADH, which generates NAD+. Once this has happened there is no longer the surfeit of cytoplasmic NADH over NAD+ from glycolysis, which is essential to drive lactate formation. Glycolysis must therefore stop at pyruvate under insulin.

This is complicated, and more complicated when considering how the two G3P dehydrogenases work together in concordance with NAD+ and NADH levels. See wiki -- https://en.wikipedia.org/wiki/Glycerol-3-phosphate_dehydrogenase , and note that Petro always uses the term 'mtG3Pdh', instead of 'GPD2'.

SIDENOTE: highlight the note about Metformin inhibiting GPD2. Another paper describing this -- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074244/ and also note this paper -- https://www.frontiersin.org/articles/10.3389/fimmu.2018.01605/full

> mtROS Are Important for T Cell Activation

> Stimulation of the T cell receptor (TCR) drives T cells into rapid proliferation and differentiation. T cell activation induces a rapid increase in mtROS production (18). Sena et al. also found that mtROS from complex III are required for CD4+ T cell activation and mitochondrial targeted antioxidant mitovitamin E attenuates IL-2 production.

> An alternative source of mtROS in mitochondria is mitochondrial glycerol-3-phosphate dehydrogenase 2 (GPD2). GPD2 oxidizes glycerol-3-phosphate to dihydroxyacetone phosphate leading to a hyper-reduced state of ubiquinone called ubiquinol in the inner mitochondrial membrane.

> Kamiński et al. found that GPD2 could directly produce ROS and accumulating ubiquinol could support ROS production at other ETC sites such as complex I (64). GPD2 depletion has been shown to inhibit mtROS production during T cell activation and decrease IL-2 expression. Mitochondrial and GPD2 induced ROS are important for T cell activation.

ie: localised loss of inflammatory response, which is charge driven (inflammation is "positive charge", or more accurately, "lack of charge motion"). Possible lack of proper immune response as a result.

Brute force addition of exogenous NAD+ will flood the cytoplasm of whatever cell manages to uptake the compound. What happens then is literally anyone's guess, given the above complications.

Personally, I cannot test nor predict any particular lasting benefit from these compounds. My current opinion is thus that it is a waste of money at best (or an opportunistic money maker!) with low dosages doing nothing to change normal metabolic function anyway, and the fate of super high doses not yet fully studied.

It should also be obvious that this is a classic "treat the symptom" move. Something goes wrong first, and thus NAD+ is depleted (proponents will cause this "normal aging process," and is only relative to NADH, which Petro notes you can also work to reduce.)

Adding more NAD+ likely does not fix the cause of relative low NAD+ to NADH.

And, of course, whilst the Niacin-type compounds have to undergo specific processing, and have vastly different effects from a straight shot of NAD+, they also have a longer history of use, so if anything, are preferred...and inexpensive.

Germs are natures recyclers and not causative of disease

Josh Lamaro — Thu, 21 Jul 2022 00:39:58 +0000

Viruses do not exist as any model currently describes them. Neither is there any real world proof that exosomes are anything more than cellular waste.

Germs are nature's recyclers, breaking down dead cells into useable energy for the benefit of all life. Germs do not cause disease.

Poisoning a cell in any way activates the microzymic components of that cell to pleomorph into what we see as "germs" which then go on to break down the dead cell, recycling its energy and breaking the waste down for removal of the toxic elements now present.

If the cell is only mildly damaged and not fatally broken, exosomic activity occurs as part of the autophagic process.

Germs are of course scientifically verified and documented. Bacteria, fungus, yeast and mold are real organisms that DO exist.
These organisms are everywhere in nature, converting all manner of death, decay and toxic waste back into life and usable energy. Germs are everywhere, in and on our bodies as well, assisting us in endless bodily processes from digestion to nutrient composition and detoxification. Germs do not CAUSE disease or harm of ANY KIND.

There are no such things as "bad" bacteria, or predatory microbes.

Our digestive system does not need help balancing its bacteria. Health within health without. Garbage in garbage out.

Whatever you feed your system, there is - ready and willing - any type of "germ" to break it down.
They are reactionary to our decisions and do not ask for anything in return, nor do they actively seek their own parasitical environment within you. Nature operates through symbiosis and synergy, not war.

The virus is an imaginary element created out of the minds of people trying to place blame for illness and disease upon something that cannot be seen in full by any means, genome sequenced (without computer model construction fantasies) or documented in real time attacking any cells, or transcribing anything to reproduce.

The Virus is a fantasy based upon various fragments of cellular waste present in every living thing (including plants) at all times without exception.

Viruses do not exist as explained by any model of health.

All so called diseases are simply various expulsion strategies raised by the body to clarify itself of the toxic food, chemicals and other substance abuses we are exposed to, all day every day.

Energy and structure and function are interdependent, at every level.

Josh Lamaro — Thu, 21 Jul 2022 00:24:35 +0000

Energy and structure are interdependent, at every level.

A given structure makes possible a certain level of useful energy, and adequate energy makes possible the maintenance of structure and function, enabling the advance to a higher and more efficient structural level.
The needs on the cellular level guide the organism’s adaptation.
Energy generates and maintains order in the system. Destruction of such order degrades the ability of cells to produce energy, by way of alteration of structure.

Any stress on the system demands energy in order for the system to overcome it.
Stress can be seen simply as an energy problem whereby the needs of the body at a given time outweigh its available resources.
When the available energy does not meet the cell’s energy requirements, if the cell is not quickly killed by stress, it will use some adaptive mechanisms, such as stopping some repair processes to reduce energy expenditure, and possibly stopping specialized functions to reduce energy needs. Typically the most energetically expensive tissues and processes are lost first eg. higher brain function.
Given the above, a state of good health could be defined as the ability to acquire, conserve, and adequately direct energy within the system to maintain metastability (adequate structure and function) through a range of varying situations.
Note that metastability may involve a stable system, despite a shift in processes. This may mean the system moves away from some advanced functions in order to remain stable in a stressful situation.

Energy, Structure and Function

Josh Lamaro — Thu, 21 Jul 2022 00:22:59 +0000

Energy as information and constrained endogenous RNA interference

jen — Mon, 28 Mar 2022 20:22:28 +0000

Found this pdf (via the creator on twitter) and am intrigued at the idea but still pondering what the document says. I just don't know enough about RNAi to be able to discuss it knowledgeably. I'm also not sure I really care either, lol. It seems too reductionist generally (although there are moments when I appreciate reductionist models of mechanism).

https://figshare.com/ndownloader/files/8392568

However, it manages to capture food, light, environment all together.

The Viral Delusion - 5 Part Series

Josh Lamaro — Fri, 25 Mar 2022 00:59:15 +0000

this fantastic 5 part summary of the problem can be found here for something like 12 bucks for the whole series.

https://paradigmshift.uscreen.io/

What is really standing in the way of pure health?

Josh Lamaro — Wed, 23 Mar 2022 02:23:27 +0000

Your body is constantly moving in the trajectory towards radiant health.

It does not attack itself, nor does it produce symptoms whos only purpose is to harm you. This is a common misconception.

Why do you believe a fever manifests? Or an increase in the production of mucus?

Why does the body hold onto water? Why does it deliver toxins and toxicants that it cannot process and release to fat cells for storage?

Why do fatigue and pain exist?

Protection and elimination.

If you have been experiencing chronic dis-ease, you must ask yourself what is blocking radiant health.
Your body is moving towards this every second of every day.

Are your cells being sent messages of survival or safety?

Are you trapped in a survival response due to trauma? Do you feel safe?

How is your home environment? Has the air quality been assessed? Are you adhering to Nature’s 8 Laws, the essential foundations of health?

Clean Air
Clean Water
Sunshine & Earthing
Rest, Sleep & Stress management
Nutrition
Movement As Medicine
Temperance
Trust, Faith & Community

Have you assessed your toxic load?

The most common blocks?

Trauma (leading to nervous system dysregulation and limbic system disorders)
Toxicity (including from poor diet, drugs, environmental toxins including but not limited to blue light, EMFs and mould)
Deficiency (usually as a result of toxicity and stress, poor intake)
Stress (physiological and psychological)
And "Infections" secondary to these, because microbes and parasites are the garbage collectors and only thrive on waste and a system weakened by stress hormones.

A reminder to remember your body is a miracle and it does not EVER betray you!

I personally know how frustrating it can feel when healing feels impossible and there is no light at the end of the tunnel, but trust when I say there is ALWAYS a reason for this.

Do you know what is standing between where you are right now and radiant health?

Fermented foods

JP9 — Mon, 21 Mar 2022 06:18:47 +0000

I hear and read a lot about the benefits of fermented food for gut/overall health. Unfortunately, it seems that everytime I try to introduce them (kimchi, blue cheese etc) a day later I slip into a depressive like state. Usually only last a day but it's noticeable. Could this be correct/common? Or am I making this up?

Michael Rintala Explains DNS from a Performance Perspective

Josh Lamaro — Wed, 05 Jan 2022 06:28:26 +0000

great video presentation:

https://vimeo.com/377091816/1be630807c